Posters from the 2000 TAMS Poster and Vendor Night

"Validation of a Fully Automated Method for GW275X and Two Metabolites Using a Custom Zymark/Tecan Robotics System and PROSPEKT On-line SPE-LC/MS/MS"
Mark C. Woodward, Gary D. Bowers, Jack Chism, Lisa St John-Williams, Glenn Smith,
GlaxoWellcome, Inc.

"Increased Proteome Coverage using a Novel Peak Trapping Interface for Nanoscale Capillary LC/MS/MS Analysis of Complex Peptide Mixtures"
Arthur Moseley1, Kevin Blackburn
1, Hans Vissers2, and Robert Bordoli3,
1GlaxoWellcome, Inc.; 2LC Packings, Amsterdam, NL; 3Micromass, Manchester, UK

"High Throughput Quantitation for Drug Mixture: LC/MS or FIA/MS?"
Kate Yu, Michael Balogh, and Jeanne Li,
Waters Corporation

"Characterization of N-Deacetylated Ketoconazole Metabolites Produced by A Recombinant Human FMO System using Triple Quadrupole and QqTOF Instruments"
Jeffrey D. Miller
1,Rosita J. Rodriguez2, Sai Y. Chang1, Takeo Sakuma3, Chuang Lu4 and Albert Li4
1
Applied Biosystems, 2Oregon State University, 3MDS Sciex, and 4In Vitro Technologies

"An Integrated Approach to Protein Identification and Quantitation based upon ICAT Analysis using Data Dependent Experiments on a QSTAR Mass Spectrometer and Novel Data Reduction Algorithms"
Lydia Nuwaysir, Ken Parker, Alpesh Patel, Austin Tomaney, Ben Halpern, Babu Purkayastha, Sasi Pillai, Dave Hawke, Shreesh Taskar, Jim Bowlby, Dan Schaeffer
Applied BioSystems

Orthogonal MALDI Quadrupole Time of Flight Mass Spectrometry: Utilization of a new tool for rapid peptide and protein identification at the femtomole level.
Mark Allen, Patricia Ilisiu, Tina Settineri, Lydia Nuwaysir, Christie Hunter
Applied Biosystems/MDS Sciex

"Pesticide Analysis at Low fmole Levels using NanoSpray"
H. Lynn, R. Thakur and I. Mylchreest,
ThermoQuest

"Mining LC/MS/MS Biotransformation Data with a Metabolism Data Browser"
I.Mylchreest, E.Hemenway, T.Mclaughlin and S.Kambouris,
ThermoQuest

"In vivo Peptide Identification From 2-D gels Using Tandem Mass Spectrometry"
Christy Raska
1, R. Marshall Pope2, and David Rubinstein3,
1Dept of Chemistry, 2LC/MS facility/Dept of Psychiatry, and 3Dept of Dermatology  
The University of North Carolina at Chapel Hill

"Mass Spectral Identification of Phosphopeptides Using a Selective Biotin-Tagging Method"
Charles A. DiTusa, R. Marshall Pope and Lee M. Graves,
Department of Pharmacology and LC/MS Facility,
The University of North Carolina at Chapel Hill

"Increased Throughput Using a Dual Prospekt System"
Charles D. James
1, John A. Dunn1, and Otto Halmingh2,
1Division of Bioanalysis and Drug Metabolism, Glaxo Wellcome Inc., RTP, NC,
2Spark Holland BV, Emmen, The Netherlands

"A Solid Sample Preparation Method Reduces Signal Suppression Effects in the MALDI Analysis of Peptides"
Michael W. Wang and Michael C. Fitzgerald,
Department of Chemistry,
Duke University

"A New MALDI-Based Method for Measuring Protein Stability"
Kendall D. Powell, Thomas E. Wales, Michael W. Wang, Peter Silinski, and Michael C. Fitzgerald,
Department of Chemistry,
Duke University

"Surfactant-Protein Binding Studies by CE and ESI-MS"
H. Gunawardena, M. Shou, and B. T. Cooper,
Department of Chemistry,
UNC Charlotte

"Time of Flight Technology Takes Off for Chromatographers"
Ritchard Parry and Fred Glisson,
Leco Corp

"GC/MS and LC/MS Analysis of Endocrine Disruptors"
Robert B. Cody, AkihikoKusai, Yoshihisu Ueda, and Tetsuichiro Morita,
JEOL

"Novel Reversed-Phase HPLC Packing for High-Throughput Screening and LC/MS"
Ritu Arora and Chris Cantelmo
MetaChem Technologies

"Analytical Method for the Determination of the Ethanesulfonic and Oxanillic Acid Degradates of Metolachlor, Acetochlor, and Alachlor in Water Using SPE and LC/ESI/MS/MS"
Louis C. Mayer, Nanzhu Shen, Robert A. Yokley, John D. Vargo, and Max W. Cheung
Novartis Crop Protection, Inc., Analytical Resources Group, Greensboro, NC

"Quantitative Determination of Two Diazinon Metabolites in Human Urine Using SPE-LC/ESI/MS/MS"
Robert A. Yokley, Nanzhu Shen, and Max W. Cheung
Novartis Crop Protection, Inc., Analytical Resources Group, Greensboro, NC

"Desorption Ionization on Silicon (DIOS) for the Analysis of Small Organic Molecules"
Peter Kitrinos, Douglas M. Sheeley, and Robert L. Johnson
GlaxoWellcome Inc.

"Proteomic Approaches for Identifying Components of the Mammalian Mitochondrial Ribosomal Small Subunit (28S) Complex"
Kevin Blackburn
1, William Burkhart1, Arthur Moseley1, Mary Moyer1, Emine Koc2, Hasan Koc2, and Linda Spremulli2
1Department of Structural Chemistry, Glaxo Wellcome Inc.
2Department of Chemistry and 3School of Public Health, Environmental Science, and Engineering, The University of North Carolina at Chapel Hill

"Characteristics and Application of Electrospray/AtmosphericSampling Glow Discharge Ionization"
Christine N. Dalton and Gary L. Glish
Department of Chemistry, The University of North Carolina at Chapel Hill

"Analysis of R,R-formoterol in Human Plasma by LC/MS/MS"
Michael Allen1, Patrick Koch2, Christian McGhee1, and Qiao Zhan1
1Triangle Laboratories, 2Sepracor, Marlborough, MA

"An Integrated Software System for Spectral Management for NMR, MS, IR AND UV-VIS and Chemical Structures"
Antony Williams, Dmitry Mityushev, Mikhail Kvasha, Vladimir Shilay
Advanced Chemistry Development (www.acdlabs.com)

"High Throughput Pharmaceutical Analysis Using Turbulent Flow Chromatography/Mass Spectrometry"
Russell Grant, Russell, Daniel Magiera, Joseph Takarewski, John Brann, Hubert Quinn,
Cohesive Technologies Inc.

"Analysis of Liver Microsome Incubations by Direct Injection Turbulent Flow LC/MS"
Joseph Takarewski, and Matthew M. Pegram,
Cohesive Technologies Inc.

"Analysis of Drugs of Abuse by Direct Injection Turbulent Flow LC/MS"
Joseph Takarewski, Dan J. Magiera,Matthew M. Pegram, and Hubert M. Quinn,
Cohesive Technologies Inc.

"Evaluation of a New Orthogonal Spray Benchtop Ion Trap Mass Spectrometer for the Identification of Bile Acid Metabolites"
Linda Lopez and Michael Zumwalt,
Agilent Technologies

"Chemical Modification of Arginine Residues for Analysis of the Tertiary Structure of CD4/HIVgp120 by Mass Spectrometry"
Christine Hager-Braun and Kenneth B. Tomer
Laboratory of Structural Biology, NIEHS

"Parallel Capillary and Narrow-bore Ultra-High flow Rate Liquid Chromatography with Mass Spectrometric (MSMS) Detection for Rapid, Direct and Sensitive Determination of Pharmaceuticals in Plasma at Extremely High Throughput"
M.K. Bayliss, D.N. Mallett, R.S. Plumb - GlaxoWellcome
D. Little - Micromass UK

"Ion/Molecule Reactions of Sodiated Poly(ethylene glycol) with Crown Ether: Kinetics of Sodium Ion Abstraction"
Sara C. McGrath and Gary L. Glish
Department of Chemistry, The University of North Carolina at Chapel Hill