Goshe Laboratory
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North Carolina State University Department of Molecular and Structural Biochemistry
 

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Our Research
  Detailed descriptions of our research.  A brief description of our research is located just to your right
Publications
A list of our selected publications
Lab Pictures
  Pictures of staff and students as well as laboratory layout and instrumentation
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Dr. Michael B. Goshe

 

 

Undergraduate Advising
By Appointment only
 
Collaborations:
Always interested in new areas of research - email us!

 

 

   
Research Interests

Area 1 - Developmental Mass Spectrometry
Bioanalytical mass spectrometry applications and method development for :
  • Proteomics
     
  • Ascertaining and quantifying sites of protein modification
     
  • Elucidating protein-protein and protein-nucleic acid interactions
Area 2 - NSF Arabidopsis 2010 project
Area 3 - Structural mass spectrometry

  • Development of novel crosslinking reagents to study low resolution protein structure and protein-protein interactions
     
  • Covalent hydrogen exchange
     
  • Identification of protein and ligand binding sites
     
  • Dynamic motions of protein and ligand interaction sites and their relation to function
MS Instrumentation  
  • Finnigan MAT900
  • (2) Finnigan LCQ Decas
  • Waters Nano-Acquity Q-TOF Premier
Contact Information

Dr. Michael B. Goshe - Assistant Professor
North Carolina State University
Department of Molecular and Structural Biochemistry
325 Polk Hall
Raleigh, NC 27695

 

e-mail: michael_goshe@ncsu.edu

Office phone: 919.513.7740
Lab phone (1): 919.513.7195 ; (2) 919.513.4348
Fax: 919.515.2047

 

 


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Last Updated 12/04/2006