Publications

  1. Meilleur F., Weiss K.L., Myles D.A. (2008) Deuterium Labeling for Neutron Structure-Function-Dynamics Analysis. Methods in Mol. Bio. In press.
  2. Weiss K.L., Meilleur F, Blakeley M.P., Myles D.A. (2008) Acta Cryst. F63:537-540. Preliminary neutron crystallographic analysis of selectively CH3-protonated, deuterated rubredoxin from Pyrococcus furiosus.
  3. Teixeira S. C. et al. (2008) Chem. Phys. 345, 133-151. New sources and instrumentation from neutron in biology.
  4. Blakeley M.P., Ruiz F., Cachau R., Hazemann I., Meilleur F., Mitschler A., Ginell S., Afonine P., Ventura O. N., Cousido-Siah A, Haertlein M., Joachimiak A., Myles D. A., Podjarny A. (2008) Proc. Natl. Acad. Sci. 105, 1844-1846. Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase.
  5. Di Costanzo L., Moulin M., Haertlein M., Meilleur F., Christianson D.W. (2007) Arch. Biochem. Biophys. 465, 82-89. Expression, purification, assay, and crystal structure of perdeuterated human arginase I.
  6. Snell E.H., van der Woerd M.J, Damon M., Judge R.A., Myles D.A., Meilleur F. (2006) Eur. Biophys. J. 35, 621-632. Optimizing crystal volume for neutron diffraction: D-Xylose Isomerase
  7. Meilleur F., Myles D.A., Blakeley M.P. (2006) Eur. Biophys. J . 35, 611-620. Neutron Laue macromolecular crystallography.
  8. Meilleur F., Snell E.H., van der Woerd M.J., Judge R.A., Myles D.A. (2006) Eur. Biophys. J. 35, 601-609. A Quasi-Laue Neutron Crystallographic Study of D-Xylose Isomerase.
  9. Blakeley M.P., Mitschler A., Hazemann I., Meilleur F., Myles D.A., Podjarny A. (2006) Eur. Biophys. J. 35, 577-583. Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase-inhibitor complex
  10. Budayova-Spano M., Bonnete F., Ferte N., El Hajji M., Meilleur F., Blakeley M.P., Castro B. (2006) Acta Cryst., F62: 306-309. A preliminary neutron diffraction study of rasburicase, a recombinant urate oxidase enzyme, complexed with 8-azaxanthin.
  11. Buffet J.C., Clergeau J.F., Cooper R.G., Darpentigny J., De Laulany A., Fermon C., Fetal S., Fraga F., Guérard B., Kampmann R., Kastenmueller A., Mc Intyre G.J., Manzin G., Meilleur F., Millier F., Rhodes N., Rosta L., Schooneveld E., Smith G.C., Takahashi H., Van Esch P., Van Vuure T.L. and Zeitelhack K. (2005). Nuclear Instruments and Methods in Physics Research Section A. 554: 392-405. Advances in detectors for single crystal neutron diffraction .
  12. Hazemann I., Dauvergne M.T., Blakeley M.P., Meilleur F., Haertlein M., Van Dorsselaer A., Mitschler A., Myles D.A.A & Podjarny A.D., Acta Cryst, D61: 1413-1417. High-resolution neutron protein crystallography with radically small crystal volumes; application of perdeuteration to human Aldose Reductase.
  13. Meilleur F., Blakeley M.P & Myles D.A.A. (2005). Hydrogen and hydration-sensitive structural biology. Editors Niimura N., Mizuno H., Helliwell J.R., Westhof E, pages 75-85. Neutron Laue analysis of hydrogen and hydration in protein structure.
  14. Blakeley M.P., Hazemann I., Mitschler A., Meilleur F., Dauvergne M.T., El Kabbani O., Cousido A., Joachimiak A., Petrova T., Myles D.A.A., Podjarny A. (2005) Hydrogen and hydration-sensitive structural biology. Editors Niimura N., Mizuno H., Helliwell J.R., Westhof E, pages 87-102. Combined high resolution X-ray and neutron crystallography to observe protonation states in human aldose reductase
  15. Bennett B.C., Meilleur F., Myles D.A., Howell E.E., Dealwis C.G. (2005) Acta Cryst. D61, 574-579. Preliminary neutron diffraction studies of Escherichia coli dihydrofolate reductase bound to the anticancer drug methotrexate
  16. Meilleur F., Dauvergne M.T., Schlichting I., Myles D.A.A. (2005) Acta Cryst. D61, 539-544. X-Ray crystallographic analysis of fully deuterated cytochrome P450cam.
  17. Meilleur F., Contzen J., Myles D.A.A., Jung C. (2004) Biochemistry. 43, 8744-8753. Structural stability and dynamics of hydrogenated and perdeuterated cytochrome P450cam (CYP101).
  18. Adamo C., Heitzman M., Meilleur F., Grand A., Cadet J. & Barone V. (2001) J. Am. Chem. Soc. 123, 7113-7117. Interplay of intrinsic and environmental effects on the magnetic properties of free radicals issuing from H-atom addition to cytosine