Meilleur Laboratory Neutrons and Structural Biology

Department of Molecular and Structural Biochemistry North Carolina State University

Neutron Sciences Directorate Oak Ridge National Laboratory


Complete list of publications here

Most recent publications

1. Li L., Shukla S., Meilleur F., Standaert R.F., Pierce J., Myles D.A., Cuneo M.J. (2017) Neutron crystallographic studies of T4 lysozyme at cryogenic temperature. Protein Sci. 26:2098-2104

2. Hiromoto T., Meilleur F., Shimizu R., Shibazaki C., Adachi M., Tamada T., Kuroki R. (2017) Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type. Protein Sci. 26:1953-1963

3. Bodenheimer A.M., O’Dell W.B., Stanley C.B., Meilleur F. (2017) Structural studies of Neurospora crassa LPMO9D and redox partner CDHIIA using neutron crystallography and small-angle scattering. Carbohydr. Res. 448:200-2042

4. O’Dell W.B., Swartz P., Weiss K., Meilleur F. (2017) Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction Acta Cryst. F73:70-78

5. Golden E., Duff A.P., Karton A., Blakeley M.P., Meilleur F., Vrielink A. (2017) An extended N-H bond driven by a conserved second order interaction orients the flavin N5 orbital in cholesterol oxidase. Scientific Reports 7, Article Number 40517

6. O’Dell W. B., Aggarwal P., Meilleur F. (2017) Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angew. Chem. Int. Ed. 56:767-770

7. Bodenheimer A. M., Meilleur F. (2016) Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states. FEBS Letters 590:4429-4438

8. O’Dell W.B., Bodenheimer A. M., Meilleur F. (2016) Neutron protein crystallography: A complementary tool for locating hydrogens in proteins.. Arch Biochem. Biophys. 602:48-60